02127nas a2200301 4500008004100000022001400041245008100055210006900136260001300205300001100218490000700229520117600236653001501412653002601427653002201453653002601475653001701501653002101518653004101539653002801580653001101608653003201619100001301651700001601664700001301680700001501693856011701708 2013 eng d a1873-635100aAnticancer, antioxidant and antibiotic activities of mushroom Ramaria flava.0 aAnticancer antioxidant and antibiotic activities of mushroom Ram c2013 Aug a375-800 v583 a
Ramaria flava is a species of edible mushroom with some bioactivity. The anticancer, antioxidant and antibiotic activities and chemical composition of R. flava ethanol extract (EE) were evaluated. The present study exhibited that the EE displayed the strongest inhibitory activity against tumor cell MDA-MB-231 with an IC50 value of 66.54 μg/mL in three tested tumor cell lines, and the inhibition percent was 71.66% at the concentration of 200 μg/mL (MTT assay). The total phenolic compounds varied among four fractions of the EE from 6.66 to 61.01 mg gallic acid equivalent (GAE) per g dry weight. Water fraction exhibited high DPPH and OH radical-scavenging activities with low IC50 values of 5.86 and 18.08 μg/mL, respectively. Meanwhile, three phenolic compounds from water fraction were also identified by HPLC. The antibiotic activities of the EE were evaluated against three microorganisms and three fungi strains by means of the agar well diffusion method and the poisoned medium technique, respectively. The EE also showed moderate antibiotic activities. These results suggest that R. flava could hold a good potential source for human health.
10aAgaricales10aAnti-Bacterial Agents10aAntifungal Agents10aAntineoplastic Agents10aAntioxidants10aCell Line, Tumor10aChromatography, High Pressure Liquid10aFree Radical Scavengers10aHumans10aInhibitory Concentration 501 aLiu, Kun1 aWang, Junli1 aZhao, Le1 aWang, Qian uhttps://mushrooms.myspecies.info/content/anticancer-antioxidant-and-antibiotic-activities-mushroom-ramaria-flava02158nas a2200409 4500008004100000022001400041245006700055210006600122260001300188300001100201490000700212520109200219653001001311653001201321653001001333653003001343653001801373653001101391653001801402653002101420653002701441653001101468653002501479653000901504653002301513653001601536653001901552653002201571653001401593653001301607653001801620100001501638700001801653700001501671700001801686856004401704 1999 eng d a0125-156200aFatal mushroom poisoning caused by Amanita virosa in Thailand.0 aFatal mushroom poisoning caused by Amanita virosa in Thailand c1999 Mar a157-600 v303 aConsumption of toxic mushrooms belonging to the genus Amanita frequently leads to severe gastrointestinal distress followed by acute hepatic failure with a fatal outcome. In Thailand, valuable information as to the locally prevalent poisonous species, the preferred habitat and the management of suspected victims of intoxication is basically non-existent. We report here 5 cases of fatal poisoning with Amanita virosa having occurred in a family residing in the northeast of Thailand who as countless others had enjoyed mushroom gathering as a pasttime. Within 4 to 6 days after ingestion of the mushrooms, all had succumbed to acute hepatic failure with subsequent hepatoencephalopathy. Treatment modalities exist in the form of penicillin and silibinin, or thioctic acid administration followed by plasmapheresis. In cases taking a lethal course apparent from the results of liver biochemistry, liver transplantation is clearly indicated. In order to prevent mushroom poisoning altogether, educating the general population to that end certainly presents the method of choice.
10aAdult10aAmanita10aChild10aCombined Modality Therapy10aFatal Outcome10aFemale10aFluid Therapy10aHealth Education10aHepatic Encephalopathy10aHumans10aLiver Failure, Acute10aMale10aMushroom Poisoning10aPenicillins10aPlasmapheresis10aProtective Agents10aSilymarin10aThailand10aThioctic Acid1 aChaiear, K1 aLimpaiboon, R1 aMeechai, C1 aPoovorawan, Y uhttps://mushrooms.myspecies.info/node/3